Biotin Interference in Clinical Immunoassays: The Dose Makes the Interference

Guofeng “George” Gao, MD, Resident Pathologist and Nam Tran, PhD, MS, FACB, Director of Clinical Chemistry and POCT
Background: Biotin, also known as Vitamin B7, is a co-factor in fatty acid metabolism, amino acid degradation, and gluconeogenesis. The recommended daily intake (RDI) for biotin is extremely low—about 30 µg/day. [...]

By | 2017-06-20T11:05:13+00:00 June 15, 2017|0 Comments

Modern Laboratory Techniques for Antiphospholipid Syndrome Testing

John Rodrigo, MD, Postdoctoral Scholar; Fabian Lara, MD, Postdoctoral Scholar; Saba Ali, MD, Resident Pathologist; Denis Dwyre, MD, Director of Hematopathology; Grace Monis, MD, Special Coagulation; Sarah Barnhard, MD, Associate Director of Transfusion; Scott Bainbridge, CLS, Special Chemistry/Toxicology Supervisor; and Nam Tran, PhD, Director of Clinical Chemistry and SARC
Background: Antiphospholipid syndrome (APS) is an autoimmune disorder [...]

By | 2017-06-20T10:45:28+00:00 May 15, 2017|0 Comments

Point of Care Testing for Blood Conservation Strategies: Finding the Right Tools Matters

Andrew D Jones, MD, MA, PGY2, Pathology and Laboratory Medicine; Fabian Lara, MD, Postdoctoral Scholar, Pathology and Laboratory Medicine; and Nam K Tran, PhD, MS, FACB, Director of Clinical Chemistry and POCT
Background: Patient Blood Management programs have, over the last several years, been working hard to reduce unnecessary red blood cell transfusions. [...]

By | 2017-06-20T10:50:39+00:00 February 15, 2017|0 Comments

Safety and Compliance Monitoring of Patients Receiving Chronic Opioid Therapy

Nam K. Tran, PhD, MS, FACB, Director of Clinical Chemistry and POCT; Scott Bainbridge, CLS, Special Chemistry/Toxicology Supervisor; and John Tsushima, CLS, Special Chemistry/Toxicology Specialist
Background: Patients receiving chronic opioid therapy (COT) should be randomly tested for elicit drug use and/or compliance with prescribed medications. [...]

By | 2017-06-20T10:58:49+00:00 February 2, 2017|0 Comments