Archive for the ‘Cool Research’ Category

UC Davis Section of General Thoracic Surgery Research Highlight

Posted on July 1st, 2016 in Cool Research, Lung Cancer | No Comments »

Periodically we highlight the research accomplishments of members of our Section of General Thoracic Surgery, as their data become available.  We will ask key simple but important questions including how they chose their research questions and most importantly how their work will impact patients.

Dr. Lisa Brown and co-authors’ paper Recurrence and Survival After Segmentectomy in Patients With Prior Lung Resection for Early-Stage Non-Small Cell Lung Cancer, was recently published first on line by the Annals of Thoracic Surgery.  The work was originally presented at the Sixty-second Annual Meeting of the Southern Thoracic Surgical Association, Orlando, FL, November, 2015.

Dr. Brown is an Assistant Professor of Clinical Surgery, and the Clinical Director of the UC Davis Comprehensive Lung Cancer Screening Program.

Lisa M. Brown, MD, MAS

Lisa M. Brown, MD, MAS

What is the question in this study?

Dr. Brown:

The goal of this study was to compare recurrence and survival in patients undergoing segmentectomy (or removal of a small part of the lung) for primary non-small cell lung cancer (NSCLC) versus those undergoing the same type of surgery for a second primary (completely new) NSCLC.

Why did you choose this research question?

Dr. Brown:

We chose this research question because we were seeing many patients who had a prior lung surgery for NSCLC presenting with a second primary (completely new) NSCLC and there is minimal data on the optimal extent of removal of lung tissue for these patients. We were interested in determining whether the long-term outcomes after segmentectomy for second primary NSCLC were as good as or at least equal to those with primary NSCLC.

What were your findings?

Dr. Brown:

In a series of 91 segmentectomies (23%) were undergoing segmentectomy for a second primary NSCLC and 70 (77%) were undergoing segmentectomy for a primary NSCLC (first lung cancer). The recurrence free survival was 61% in those undergoing segmentectomy for a second primary NSCLC and 84% in those undergoing segmentectomy for a first primary NSCLC (p=0.09). The 5-year survival was 55% in those with second primary NSCLC and 65% in those with primary NSCLC (p=0.4).

How might the findings help patients?

Dr. Brown:

We concluded that segmentectomy is a reasonable resection strategy for patients with a second primary NSCLC as the long term survival is similar to those with primary NSCLC and lung tissue is preserved when compared to lobectomy.

Learn more on how to support the research of the UC Davis Section of General Thoracic Surgery.

New Point-of-Care App, PulmaCalc PPO, Predicted Post-operative Pulmonary Function Calculator

Posted on July 16th, 2013 in Blow Your Mind Technology, Cool Research, Lung Cancer | No Comments »

Brought to you by the UC Davis Section of General Thoracic Surgery: PulmaCalc PPO is a predicted post-operative pulmonary function calculator.  This unique point of care app, is ideal for health care providers, trainees and patients interested in patient centered medicine to easily calculate predicted post-operative (PPO) pulmonary function based on known pulmonary function test (PFT) values and knowledge of the extent of anatomic lung tissue removed.

The easy to use, intuitive interface allows the user to determine the PPO pulmonary function after segmentectomy, lobectomy or pneumonectomy, using known values for Forced Expiratory Volume in 1 second (FEV1) and Diffusing Capacity of the Lung for Carbon Monoxide (DLCO).

For segmentectomy and lobectomy, the user may utilize the anatomic graphic feature or the slide bar to input the number of anatomic segments removed for calculation.

For pneumonectomy a slide bar for the fraction of lung perfusion measured by quantitative radionuclide ventilation/perfusion (V/Q) scan can be used to determine PPO FEV1and DLCO.

Additional tabs describe the role for calculating PPO pulmonary function and the evidence-based medicine behind it.

This application is for informational purposes only and is not intended as a substitute for medical care, advice or professional services.

Available for the iPhone and iPad

To download PulmaCalc PPO click here:

To trouble shoot or additional questions contact:


PulmaCalc in iTunes