ChestHealth

UC Davis thoracic surgery providers are helping to evolve healthcare to emphasize patient value.  Patient value not only includes traditional outcomes such as  cure of cancer and amelioration of pain, but also by the effects on quality of life, function after surgery, and most importantly, what immediate outcomes are important to patients and their families.

Transparency in outcomes is important for patients and their families, referring physicians and other stakeholders to make informed decisions on which health systems provide optimal care.  The clinical outcomes of the UC Davis Section of General Thoracic Surgery are tracked by several validated national quality databases and evaluation organizations including the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP^®), The ACS Committee on Cancer Quality Improvement Program (CQIP^®), the Society of Thoracic Surgeons (STS) General Thoracic Surgery Database and the LeapFrog Group.  These bodies compare medical institutions outcomes to national benchmarks and determine how individual institutions rank.

• The ACS NSQIP^® comparisons determine if an institution’s results are in line with its national peers (As Expected), underperform its peers (Needs Improvement) or out perform its peers (Exemplary).
• The CQIP^® compares cancer specific results between the Commission on Cancer accredited medical centers.  Medical centers listed in the comparisons are only national health systems with established quality cancer care infrastructure.
• The STS Database measures the outcomes of American Board of Thoracic Surgery eligible or certified physicians, and therefore measures the thoracic surgery outcomes of the “best of the best” surgeons in the nation.
• The LeapFrog Group determines the Highest Quality of Care Rating by surveying participating hospitals and measuring their outcomes.  A hospital can achieve a Highest Quality of Care Rating by:

-         Participating in the Leapfrog Survey

-         Performing ≥ 13 esophagectomies during the survey year

-         All of the esophagectomies performed by high-volume surgeon (≥ 2 esophagectomies/year)

Below are our UC Davis Section of General Thoracic Surgery Outcomes as measured by the most recent national quality assurance measures:

2013 ACS NSQIP^® All Procedures

Where Mortality is the rate of surviving the hospital experience after an operation; pneumonia is a lung infection acquired during the hospitalization; ventilator > 48hrs refers to the time on a breathing machine after an operation; morbidity is the accumulative complications after an operation; unplanned intubation is the need for a breathing tube to be put back in after an operation; deep venous thrombosis is a blood clot in the arms or legs that may develop after an operation; urinary tract infection is an infection often from a bladder catheter that is placed for an operation; return to the operating room is an unplanned re-operation after the intended or index operation.

2009-2011 CQIP^® Lung Cancer Resection

30-Day Mortality is the rate of not surviving 30 days after an operation, even after having gone home.  Lung Resection is the surgical removal of part of the lung such as a lobectomy or the entire lung on one side such as a pneumonectomy.  The most recent available data for CQIP^® is for the years 2009-2011.

STS General Thoracic Surgery Database (2011-2013)

Where Discharge Mortality is the rate of not leaving the hospital alive after the operation, and 30-Day Mortality is the rate of not surviving 30 days after an operation, even after having gone home.

LeapFrog Group Ratings for Esophageal Resection (2013)

 4-Bar, Best Odds for Survival Ranking or Highest Quality of Care Rating: Top in the Sacramento region.

Where 4-Bars (Highest Quality of Care Rating) means the patient has the best chances of surviving an esophageal resection.  An esophageal resection or Esophagectomy is a surgery to remove the esophagus and replace it with the stomach or colon and is most commonly performed for cancer, though sometimes it needs to be performed for very extreme non-cancer disease.

The LeapFrog Highest Quality of Care Rating determines quality or value based on the volume, or the number of procedures performed.  The thinking is that having experience with a procedure refines quality outcomes and promotes value.  This volume-outcome relationship has been demonstrated in the scientific literature (Birkmeyer et al, New Engl J of Med, 2002) for both esophageal cancer surgery (Esophagectomy) as well as lung cancer surgery otherwise called lung  resection, such as lobectomy and pneumonectomy.

Since 2008 our UC Davis Section of General Thoracic Surgery has performed over 100 esophagectomies and over 250 lobectomy and pneumonectomies.  Seventy percent of our lung resections are performed minimally invasively either by Video-Assisted Thoracic Surgery (VATS) or by Robot.

Patient-centered value outcomes, as mentioned above, have a lot to do with the skill of the surgeon and the surgeon’s volume based experience.  However the central driver of quality outcomes is careful planning, attention to detail, and scientific evidence based best-practice treatment algorithms that are followed in consensus by the entire care team.  Care processes or pathways that are patient/family-focused, foster coordination and communication amongst all providers can promote efficiency and improve results that are important to patients (Vanhaecht et al, Health Serv Mange Res, 2007).

At UC Davis, we have developed novel evidence based post-operative care pathways for esophagectomy (Cooke et al, Society of Thoracic Surgeons 49^th Annual Meeting, 2013) and lung resection as well as Respiratory Therapy pathways that are designed to prevent pneumonia, need for replacement of a breathing tube and pronged need for a breathing tube (Tanner-Corbett…Cooke et al, 14^th World Conference on Lung Cancer, 2011), and in effect, “stack the deck” in the patients favor to achieve important top clinical outcomes.

We are now creating patient-centered pathways to foster patient engagement and activation, so that patients and their families are more participatory in their care, and help make the outcomes that are most important to them a reality.  These research endeavors are supported by a grant from the Patient-Centered Outcomes Research Institute.  To learn more click here.

With our evolving health care system, the definition of quality has matured from not only advanced technology that is available, but also the value in outcomes that the patient experiences, and maximization of the outcomes that are most important to patients and their families.  At UC Davis we are proud to be innovators and leaders in quality healthcare.

On Thursday, June 19^th at 5 PM Pacific/ 8 PM Eastern, Dr. David Tom Cooke (Twitter@UCD_ChestHealth) will moderate the #LCSM Tweet Chat. The topic: “What are clinical and functional outcomes after lung cancer surgery that are most important to patients & their families?” 

We will partner with #LCSM (#Lung Cancer Social Media; Twitter@LCSMchat), a TweetChat patient education platform, to engage the lung cancer community.  On Twitter, stakeholders tweet using the hashtag #LCSM to flag microblogging discussions of lung cancer treatment, research, and numerous other lung cancer patient focused issues.  The #LCSM TweetChat is a set time when people interested in lung cancer gather virtually via Twitter, and with guidance from a moderator, chat about specific patient-centered topics in lung cancer.  The bimonthly #LCSM TweetChats are an hour long. Hundreds of #LCSM tweets are sent during the chat. Participants in the TweetChat are international, and include patients, family members, researchers, multidisciplinary medical professionals and advocates.  All tweets that include the #LCSM hashtag during the specified hour are recorded in a TweetChat transcript and made available online.

The June 19^th #LCSM Tweet Chat moderated by Dr. Cooke is part of his Patient Centered Outcomes Research Institute funded project entitled “Empowering Patients and Their Families to Improve Outcomes That Are Most Important to Them after Lung Cancer Surgery”.

Patient-centered outcomes research (PCOR) seeks to assist stakeholders (patients, their family members , friends and care providers) communicate and make informed healthcare decisions, allowing multiple voices to be heard in assessing the value and efficacy of healthcare options.  PCOR answers patient-centered questions such as: “What can I do to improve the outcomes that are most important to me?” and “How can clinicians and the care delivery systems they work in help me make the best decisions about my health?” (http://www.pcori.org/). Dr. Cooke is seeking to bring the concept of PCOR to thoracic surgery research and improve outcomes for patients undergoing lung cancer surgery.

Lung cancer surgery, specifically lobectomy (removing 1/5 of the lung) and pneumonectomy (removing the entire lung on one side), are the gold-standard therapies for early and locally advanced lung cancer.  However, lung cancer surgery is high-risk and associated and can be associated with an elevated risk of death (mortality), complications, and prolonged hospital length-of-stay and hospital readmissions.  In U.S. hospitals, national 30-day mortality after lobectomy ranges between 4-6% and 11-17% after pneumonectomy (Birkmeyer et al, N Engl J Med. 2002).  Dr. Cooke is investigating if patient and family participation can drive improvements in lung cancer surgery outcomes, leading to the creation of successful after-surgery patient care protocols that will translate the good results of high performing medical centers to all types of institutions performing lung cancer surgery.  Active engagement of patients and their families in the after-surgery clinical care process may improve the quality of life and overall survival of patients surgically treated for lung cancer.

By having a conversation with the #LCSM community, #LCSM will put to light what after-surgery clinical and functional outcomes are most important to patients and family and friends after surgery for lung cancer.  Talk about the communication between the patient, family/friends & healthcare providers after their operation and during their hospital stay. Were there any problems and if so how can surgeons, patients and all stakeholders improve the communication?  And finally, what changes in the lung cancer surgery care process are needed to achieve the clinical and functional goals that are important to patients and their family/friends?

With the above goals, here are the 3 questions that will be discussed during the June 19^th Tweet Chat:

What are clinical and functional outcomes after #lungcancer surgery that are most important to patients & families? #LCSM

T1 What post-op clinical and functional outcomes are most important to you (patients & family) after #surgery for #lungcancer. #lcsm

T2 Talk about communication between the patient, family & HCPs after operation and during hospital stay. Problems/how to improve? #lcsm

T3 ? changes in #lungcancer surgery care process are needed to achieve clinical/functional goals important to patients & family. #lcsm

Here is more info on how to participate in the #LCSM Chat.  To learn more about how to support the Section of General Thoracic Surgery’s innovative research, click here.

Ending Lung Cancer in Women – Turning the Country Turquoise

What We Should Know During National Women’s Health Week

By Elizabeth A David, MD

General Thoracic Surgeon

UC Davis Section of General Thoracic Surgery

Each October, the US turns pink to raise awareness for breast cancer.  Football fields are painted pink, women are reminded to do breast self-exams, and have their annual screening mammograms.   Approximately, 40,000 women will die of breast cancer in 2014 and 232,670 new cases of breast cancer will be diagnosed (^1,2).    Breast cancer advocates are to be congratulated on their successes with raising awareness and lung cancer advocates, physicians, and patients should take note of their strategies.

Lung cancer remains the number one cause of cancer-related deaths in the US.  It is estimated in 2014, that 72,330 women will die of lung cancer and 108,210 women will be diagnosed with lung cancer (^1,2).  As many of us know, a large number of lung cancer cases are related to tobacco use and for this reason carries a stigma in society which can interfere with patients seeking treatment.  What many people don’t know is that lung cancer in women who have never smoked is on the rise.  Dana Reeve, widow of Christopher Reeve, was one example.  Mrs. Reeve was diagnosed at age 44 and died within a year of her diagnosis; she had never smoked.  Although the stigma of lung cancer discouraged her, Mrs. Reeve became an advocate for other lung cancer patients and a strong supporter of the American Cancer Society. 

Unfortunately for all patients with lung cancer, symptoms are rare for early-stage disease when a cure is possible.  Generally by the time patients have symptoms, their disease is advanced and more difficult to treat and or cure.   Lung cancer screening has been shown to provide a 20% reduction in lung cancer specific death rates when high-risk patients were screened with annual low-dose CT scans of the chest (³).    High-risk individuals have been defined as those 55-74 years old, with a smoking history of 30 years or more and former smokers who had quit within the last 15 years.   These statistics do not help our female patients who have never smoked though.   Research is continuing to look at blood tests and other tests that can be used as screening exams for asymptomatic patients. 

What can you do to help yourself or someone you love?  If you are an individual who is high-risk for lung cancer (i.e. you are currently smoking and have a 30 pack-year history or you quit within the last 15 years), ask your doctor about lung cancer screening with a low dose CT scan.  For information on our UC Davis Comprehensive Lung Cancer Screening Program please call 916 734-0655 to schedule a low dose CT for lung cancer screening.  Our lung cancer screening program is a Lung Cancer Alliance Screening Center of Excellence.  If you have a first degree-relative with lung cancer, talk to your doctor about your risk and whether or not screening is appropriate.  Please do not ignore symptoms of cough, chest pain or unexplained weight loss – talk to your doctor. 

If you would like more information about women’s lung health, go to www.lungforce.org.  We are proud to partner witht the American Lung Association in California, especially during this National Women’s Health Week.  The American Lung Association is launching a national campaign to raise awareness for women’s lung health, decrease the stigma of lung cancer and COPD and to promote research.  Join the effort by wearing Turquoise, the signature color for the Lung Force lung cancer and COPD campaign, and telling people why you are doing so.  Remember, when your doctor mentions your annual mammogram to ask about your risk of lung cancer and whether or not screening is appropriate. 

References:

1. http://www.cancer.org/acs/groups/content/@research/documents/document/acspc-041775.pdf
2. http://www.cancer.org/acs/groups/content/@research/documents/document/acspc-041776.pdf
3. http://www.nejm.org/doi/full/10.1056/NEJMoa1102873

On December 30^th , via a publication in the Annals of Internal Medicine found here, the United States Preventive Services Task Force (USPSTF) announced they recommend annual screening for lung cancer with low-dose computed tomography (LDCT) in adults aged 55-80 years who have a 30 pack-year smoking history (the number of years smoking x number of packs per day, for example 2 pack/day smoking habit for 15 years equals 30 pack-years, or 1 pack/day smoking habit for 30 years also equals 30 pack-years) and currently smoke or have quit within the past 15 years.  The USPSTF also recommended that screening should discontinue once a person has stopped smoking for 15 or more years, or has developed a medical condition that would preclude curative surgery if a lung cancer was to be found.

These ground breaking recommendations are a follow-up to the USPSTF recommendations released July 29^th, 2013.  Since their July 29^th announcement, the USPSTF reviewed multiple data including US and European randomized clinical trials, and employed population modeling studies commissioned from the Cancer Intervention and Surveillance Modeling Network (CISNET).  The USPSTF’s support of lung cancer screening by LDCT is a departure from their last report in 2004, where they found no evidence in support of lung cancer screening by LDCT or chest x-ray or sputum analysis.

So what is the USPSTF?  The USPSTF is an “independent panel of experts in primary care and prevention that systematically reviews the evidence of effectiveness and develops recommendations for clinical preventive services.” (http://www.ahrq.gov/clinic/uspstfix.htm Agency for Healthcare Research Quality).  The USPSTF offers graded recommendations from A (high certainty that the net benefit [of an intervention] is beneficial) to D (recommendation against [the intervention]).  There is an alternative grade called “I” or insufficient evidence.  The USPSTF provides a grade “B” recommendation for lung cancer screening with LDCT; randomized clinical trials looking at LDCT for lung cancer screening provides “moderate certainty” of the benefit to a high-risk population.

So why are the USPSTF recommendations on lung cancer screening important?  Currently very few insurance plans, including Medicare or Medicaid, cover the costs of lung cancer screening.  Most asymptomatic patients who fit the high risk group defined above must pay out of pocket expenses if they want a LDCT specifically for the purposes of lung cancer screening.  Lesser et al demonstrated (Lesser et al, Ann Fam Med. 2011) that from 2007 to 2009 the USPSTF recommended 15 preventative interventions for adults aged 65 years and older.  Medicare partially covered 93% of the recommended services.  In the same time frame, USPSTF recommended against 16 preventive services, and Medicare partially covered only 44% of those services.  So although the USPSTF recommendations, per their own disclaimer, “are independent of the US Government”, the Centers for Medicare and Medicaid Services (CMS) take their recommendations seriously when determining clinical services coverage.

What information is the USPSTF using for their recommendations?  Although the USPSTF reviewed multiple studies and randomized clinical trials, the largest study they looked at is the National Lung Screening Trial (NLST).  The NLST was a US, academic, multi-hospital randomized clinical trial comparing chest X-ray to LDCT for screening in patients considered high risk (aged 55-74, 30 pack-year smoking history, current smoker or quit within 15 years at point of eligibility).  Patients underwent three annual screening exams.  The results demonstrated that LDCT reduced death from lung cancer by 20% compared to chest X-ray, and overall death from all causes by 6.7% compared to chest X-ray.  70% of the lungs cancers found by LDCT were stage I or II, or the earliest most curable stage.

Why is lung cancer screening important?  Currently 75% of patients who are diagnosed with lung cancer are diagnosed at stage III or IV, or locally advanced or metastatic stages.  Although there have been improvements in targeted molecular therapy as illustrated here, long term survival for patients with advanced stage lung cancer is difficult.  As mentioned above, 70% of the lung cancers found by screening LDCT were early stage tumors, where 5 year survival is 75-80%.  This is an incredible “stage-shift” which will have marked benefits on society.

What else did the USPSTF say?  The USPSTF highly recommended that smoking cessation be incorporated into any screening program.  This brings up the important point; any lung cancer screening program should be a comprehensive screening program.  What does that mean?  It means that a patient should enter the appointment with a referral from a primary-care provider.  This allows for communication of results, and continuity of care.  All active smokers should undergo smoking cessation counseling.  Patients with abnormal lung findings should have the opportunity to receive counseling and guidance form a lung cancer screening program clinician.  In addition the screening program should be multidisciplinary, and have frequent continuous quality improvement meetings to oversee the efficacy and results of the program.  Our UC Davis Comprehensive Lung Cancer Screening Program fits theses criteria, and is comprehensive in its design and implementation.

Is there any controversy to the USPSTF recommendations?  Not controversy, but the USPSTF recommendations focus on a group that is defined as high risk (aged 55-80, 30 pack-year smoking history, current smoker or quit within 15 years), but what about patients that do not fit the smoking criteria but are also at risk for lung cancer?  Those patients include, but not limited to those individuals who have been exposed to asbestos, have COPD, high levels of radon exposure, history of interstitial lung disease and a family history of lung cancer.  The National Comprehensive Cancer Network recommends LDCT screening in patients who are aged 50-74, 20 pack-year smoking history and have one additional risk factor.  Risk factors include the following:  personal lung cancer history (>5 years), family history of lung cancer (first degree relative), chronic lung disease, and carcinogen exposure (excluding second hand smoke exposure).  We have also incorporated the NCCN guidelines into our UC Davis Comprehensive Lung Cancer Screening Program.

How can I learn more about lung cancer screening LDCT?  There are a number of patient-centered resources.  The National Cancer Institute has a NLST Patient and Physician Guide.  The American Lung Association offers an online patient-centered tool found here, that helps patients determine if they are candidates for LDCT lung cancer screening.  A great social media community is #LCSM, which regularly has Twitter chats that discuss lung cancer issues, and has an associated blog.  Finally our representatives from our UC Davis Comprehensive Lung Cancer Screening Program are available to answer questions at 916-734-0655.

Medicine is evolving where the focus expands to not just state of the art technology and procedures to care for our patients, but also what value can medicine provide to patients.  That value is defined by not just the overarching goals of therapy, i.e. cure of cancer, resolution of infection, amelioration of pain, but also by the effects on quality of life, function after surgery, and most importantly, what immediate outcomes are important to patients and their families.

For a potential patient and their family, transparency in provider outcomes is key.  The patient-centered outcomes of the UC Davis General Thoracic Surgery Program are tracked by several quality databases and evaluation organizations including the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP^®), the Society of Thoracic Surgeons (STS) General Thoracic Surgery Database and the LeapFrog Group.  These bodies compare medical institutions outcomes to national benchmarks and determine how individual institutions rank.  For example, in the case of ACS NSQIP, comparisons determine if an institution’s results in eight measured outcomes are in line with its national peers (As Expected), underperform its peers (Needs Improvement) or out perform its peers (Exemplary).

Below are our UC Davis Thoracic Surgery Program Outcomes as measured by the most recent national quality assurance measures:

2012 ACS NSQIP^®

Where Mortality is the rate of surviving the hospital experience after an operation; pneumonia is a lung infection acquired during the hospitalization; ventilator > 48hrs refers to the time on a breathing machine after an operation; morbidity is the accumulative complications after an operation; unplanned intubation is the need for a breathing tube to be put back in after an operation; deep venous thrombosis is a blood clot in the arms or legs that may develop after an operation; urinary tract infection is an infection often from a bladder catheter that is placed for an operation; return to the operating room is an unplanned re-operation after the intended or index operation.

STS General Thoracic Surgery Database (2010-2012)

Where Discharge Survival is the rate of leaving the hospital alive after the operation, and 30-Day Survival is the rate of surviving 30 days after an operation, even after having gone home.

LeapFrog Group Ratings for Esophageal Resection (2013)

 4-Bar, Best Odds for Survival Ranking or Highest Quality of Care Rating: Top in the Sacramento region.

Where 4-Bars (Highest Quality of Care Rating) means the patient has the best chances of surviving an esophageal resection.  An esophageal resection or Esophagectomy is a surgery to remove the esophagus and replace it with the stomach or colon and is most commonly performed for cancer, though sometimes it needs to be performed for very extreme non-cancer disease.

The LeapFrog Group determines the Highest Quality of Care Rating by surveying participating hospitals and measuring their outcomes.  A hospital can achieve a Highest Quality of Care Rating by:

-       Participating in the Leapfrog Survey

-       Performing ≥ 13 esophagectomies during the survey year

-       All of the esophagectomies performed by high-volume surgeon (≥ 2 esophagectomies/year)

The LeapFrog Highest Quality of Care Rating determines quality or value based on the volume, or the number of procedures performed.  The thinking is that having experience with a procedure refines quality outcomes and promotes value.  This volume-outcome relationship has been demonstrated in the scientific literature (Birkmeyer et al, New Engl J of Med, 2002) for both esophageal cancer surgery (Esophagectomy) as well as lung cancer surgery otherwise called pulmonary resection, such as lobectomy and pneumonectomy.

Since 2008 our UC Davis General Thoracic Surgery Program has performed 100 esophagectomies and over 200 lobectomy and pneumonectomies.

Patient-centered value outcomes, as mentioned above, have a lot to do with the skill of the surgeon and the surgeon’s volume based experience.  However the central driver of quality outcomes is careful planning, attention to detail, and scientific evidence based best-practice treatment algorithms that are followed in consensus by the entire care team.  Care processes or pathways that are patient/family-focused, foster coordination and communication amongst all providers can promote efficiency and improve results that are important to patients (Vanhaecht et al, Health Serv Mange Res, 2007).

At UC Davis, we have developed novel evidence based post-operative care pathways for esophagectomy (Cooke et al, Society of Thoracic Surgeons 49^th Annual Meeting, 2013) and lung resection as well as Respiratory Therapy pathways that are designed to prevent pneumonia, need for replacement of a breathing tube and pronged need for a breathing tube (Tanner-Corbett…Cooke et al, 14^th World Conference on Lung Cancer, 2011), and in effect, “stack the deck” in the patients favor to achieve important top clinical outcomes.

With our evolving health care system, the definition of quality has matured from not only advanced technology that is available, but also the value in outcomes that the patient experiences, and maximization of the outcomes that are most important to patients and their families.  Transparency in provider outcomes helps patients make informed decisions on how their care should be directed.

The section of General Thoracic Surgery at UC Davis is offering Robotic Thoracic Surgery to further enhance our top regional minimally invasive thoracic surgery program. 

 What is robotic surgery? 

Robotic surgery is performed in much the same way that minimally invasive thoracic surgery (VATS) is performed.  It involves the use of small incisions, a video camera and a surgical robot.  The surgical robot is under the control of your surgeon at all times.  One of the many advantages of the surgical robot is the ability to have wristed articulation inside the chest, almost like having a surgeon’s hand inside your chest (without having a large incision).  The robot also provides exceptional optics, surgeon control of all instruments and is ideal for visualization in tight spaces like the middle of the chest¹.  Additionally, robotic lung resection is associated with a shorter need for narcotic pain medication after surgery and an earlier return to usual activities when it is compared to traditional VATS lung resections².  When compared to VATS, robotic surgery has been found to have similar complication and death rates, as well as similar long-term survival for cancer patients undergoing cancer resections³. 

For what surgeries is the robot being used? 

We are currently using the surgical robot for:

• mediastinal tumors (tumor in the middle of the chest)
• lung biopsy
• lung lobectomy (removal of parts of the lung)
• removal of masses from the chest
• procedures of the diaphragm

The UC Davis Robotic Thoracic Surgery Program offers unprecedented new value and quality to our patients

UC Davis Robotic Thoracic Surgery Team:

Dr. Elizabeth A. David

Dr. David Tom Cooke

Robin Kelly, PA-C

References

1. Cerfolio EJ, Bryan AS, Minnich DJ.  Operative techniques in robotic thoracic surgery for inferior or posterior mediastinal pathology.  . J Thor and CV Surgery 2012; 143 (5) 1138-43.
2. Louie BE, FarivarAS, Aye RW et al. Early Experience with Robotic Lung Resection Results in Similar Operative Outcomes and Morbiditiy When Compared with Matched Video-Assisted Thoracoscopic Surgery Cases.  Ann Thor Surg 2012 May Vol 93 (5) 1598-1605.
3. Park BJ, Melfi F, Mussi A et al. Robotic lobectomy for non-small cell lung cancer (NSCLC): Long-term oncologic results. J Thor and CV Surgery 2012; 143 (2) 383-9.

UC Davis Comprehensive Lung Cancer Screening Program

(CLSP)

UC Davis CLSP is a multidisciplinary program for comprehensive lung cancer screening.  The innovative program provides low-dose chest computed tomography (LDCT) technology to detect lung cancer early in its most treatable form in those individuals at the highest risk for lung cancer.   The groundbreaking National Lung Screening Trial (NLST) clearly shows that screening with LDCT scans reduces the risk of dying from lung cancer in heavy smokers by 20% compared to screening with simple chest X-rays.  (N Engl J Med. 2011).

The UC Davis Comprehensive Lung Cancer Screening Program addresses the recent recommendations released on July 29, 2013 by the United States Preventive Services Task Force (USPSTF) for annual LDCT scans to screen individuals who are at high risk for lung cancer.  To serve our patients in the program, we use a multidisciplinary team of Radiologists, Thoracic Surgeons, Pulmonologists, Pathologists, Medical Oncologists and Radiation Oncologists to develop a best-practice, patient-centered plan.

Who Do We Screen?

      UC Davis CLSP serves a specific high-risk population for lung cancer.  This population is defined by the results of the multi-institution NLST, the USPSTF recommendations and the National Comprehensive Cancer Network (NCCN) and includes the following:

a)     High-Risk Patients: Group 1

 i.   Current or former smokers 55-80 years of age;

ii.   Smoked the equivalent of one pack of cigarettes a day for at least 30 years;

iii.   If a former smoker, he/she should have quit within the previous 15 years.

b)     High-Risk Patients:  Group 2

i.     Current or former smokers 50-80 years of age;

ii.    Smoked the equivalent of one pack of cigarettes a day for at least 20 years;

iii.   Have one additional lung cancer risk factor.  Risk factors include the following:   personal lung cancer history (>5 years), family history of lung cancer (first degree relative), chronic lung disease, and carcinogen exposure (excluding second hand smoke exposure).

How do I Schedule an Exam?

We would be happy to assist you with lung cancer screening or answer additional questions through our Radiology Department. Their phone number for scheduling is 916-734-0655. We will need a referral from your Primary Care Provider or PCP. The referral can be faxed to 916-703-2254.

Insurance does not currently pay for lung cancer screening, and an out-of-pocket price for the exam is $375.

The results will be reported back to your PCP. Should an abnormality be found which requires further evaluation; our UC Davis CLSP Practitioners, including Pulmonologists and/or Thoracic Surgeons, will assist you, if your PCP wishes to consult them.

In addition if interested, we can offer you advice and help on strategies to stop smoking.

Thank you again for choosing UC Davis CLSP!

Brought to you by the UC Davis Section of General Thoracic Surgery: PulmaCalc PPO is a predicted post-operative pulmonary function calculator.  This unique point of care app, is ideal for health care providers, trainees and patients interested in patient centered medicine to easily calculate predicted post-operative (PPO) pulmonary function based on known pulmonary function test (PFT) values and knowledge of the extent of anatomic lung tissue removed.

The easy to use, intuitive interface allows the user to determine the PPO pulmonary function after segmentectomy, lobectomy or pneumonectomy, using known values for Forced Expiratory Volume in 1 second (FEV₁) and Diffusing Capacity of the Lung for Carbon Monoxide (DLCO).

For segmentectomy and lobectomy, the user may utilize the anatomic graphic feature or the slide bar to input the number of anatomic segments removed for calculation.

For pneumonectomy a slide bar for the fraction of lung perfusion measured by quantitative radionuclide ventilation/perfusion (V/Q) scan can be used to determine PPO FEV₁and DLCO.

Additional tabs describe the role for calculating PPO pulmonary function and the evidence-based medicine behind it.

This application is for informational purposes only and is not intended as a substitute for medical care, advice or professional services.

Available for the iPhone and iPad

To download PulmaCalc PPO click here:

https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewSoftware?id=670782795&mt=8

To trouble shoot or additional questions contact:

scott@fouraxisapps.com

In July 2009 a new lung cancer staging system was revealed: The 7^th edition of the Tumor/LymphNode/Metastasis (TNM) classification. The 7^th edition TNM classification is a result of the International Staging Committee (ISC) created by the International Association for the Study of Lung Cancer (IASLC), resulting in the IASLC Lung Cancer Retrospective Staging Project.¹

            The ISC compiled clinical data on over 100,000 patients diagnosed with NSCLC and SCLC between 1990 and 2000, making the patient population examined 20 times the size of the 1997 analysis.  All components of the staging system were considered for upgrading, with the majority of changes occurring in the T and M components.¹

            The 6^th staging edition divided tumors into two size groups: T1 < 3cm in diameter, and T2 ≥ 3cm in diameter.  However, most thoracic surgeons and medical oncologists can anecdotally attest that the biologic behavior of node negative tumors that are 6-7cm, behave differently then 3cm node negative tumors, despite both being in the same broad T2 grouping.  The ISC confirmed this assumption.  Results suggested that new size groupings should be created of 2, 3, 5 and 7cm.  5 year survival rates for the pathologic groupings with negative nodes and no metastasis were 77% for T1 ≤ 2cm, 71% for T1 > 2cm and ≤ 3cm, 58% for T2 > 3cm and ≤ 5cm, 49% > 5cm and ≤ 7cm and 35% for T2 > 7cm.  Subsequently, the ISC recommended subclassifying T1 into T1a (≤ 2cm) and T1b (>2cm and ≤3cm) and subclassifying T2 into T2a (> 3cm but ≤ 5cm or tumor with any other T2 descriptors, but ≤ 5cm) and T2b (> 5cm but ≤ 7cm), and reclassify T2 tumors > 7cm to T3.²

                        No formal changes were recommended for nodal staging.  Malignant pleural effusion was reclassified to M1a.  The ISC found that extrathoracic metastasis had poorer prognosis than intrathoracic metastasis.  M1 was therefore sub-classified to M1a for additional tumors in the contralateral lung, malignant pleural and pericardial effusions, and nodular pleural dissemination, and M1b for extrathoracic metastasis.^3,4

            The new stage groupings are as follows:  T2b tumors ((> 5cm but ≤ 7cm) that are N0M0 are upstaged from IB to IIA; T2a tumors (≤ 5cm) that are N1M0 are down staged from IIB to IIA, and T4 tumors that are N0/1 are down staged to IIIA.  Restaging the patient population in the study based on the proposed 7^th TNM edition, found a pathologic 5 year survival rate 73% for IA, 58% for IB, 46% for IIA, 36% for IIB, 24% for IIIA, 9% for IIIB and 13% for IV.⁵

            The 7^th edition TNM staging system for NSCLC is an exciting accomplishment, and will help the clinician to better understand the outcomes of lung cancer and offers an exciting advance to our specialty. 

1. Rami-Porta R, Crowley JJ, Goldstraw P.  The revised TNM staging system for lung cancer.  Ann Thorac Cardiovasc Surg. 2009 Feb;15(1):4-9.

2. Rami-Porta R, Ball D, Crowley J, et al.  The IASLC Lung Cancer Staging Project: proposals for the revision of the T descriptors in the forthcoming (seventh) edition of the TNM classification for lung cancer. J Thorac Oncol. 2007 Jul;2(7):593-602.

3. Rusch VW, Crowley J, Giroux DJ, et al.  The IASLC Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming seventh edition of the TNM classification for lung cancer.  J Thorac Oncol. 2007 Jul;2(7):603-12.

3. Postmus PE, Brambilla E, Chansky K, et al.  The IASLC Lung Cancer Staging Project: proposals for revision of the M descriptors in the forthcoming (seventh) edition of the TNM classification of lung cancer.  J Thorac Oncol. 2007 Aug;2(8):686-93.

4.  Goldstraw P, Crowley J, Chansky K, et al.  The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours.  J Thorac Oncol. 2007 Aug;2(8):706-14. Erratum in: J Thorac Oncol. 2007 Oct;2(10):985.

5. Rusch VW, Asamura H, Watanabe H, et al.  The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer.  J Thorac Oncol. 2009 May;4(5):568-77.

The UC Davis Lung Cancer Chat Room is an interactive meeting of learning and support for patients, families, friends and caregivers affected by lung cancer.

This support group is proudly sponsored by the UC Davis Comprehensive Cancer Center.

The UC Davis Lung Cancer Chat Room provides a time for education, sharing and an opportunity to connect face-to-face with people who can relate the realities of lung cancer. Special guest speakers are invited to give presentations on topics of interest to patients. Educational and support materials are provided.

3rd Thursday of each month
10:30am-12:00pm
UC Davis Comprehensive Cancer Center
4501 X St. Sacramento, CA
Room #1103

For more information about this group, please contact Jena Cooreman, LCSW at 916-734-5198

2013 Calendar of Group Speakers
DateSpeaker/Topic

February 21st

David Copenhaver, MD, MPH
Director of Cancer Pain, Division of Pain Medicine
Pain Management

March 21st

David Tom Cooke, MD, FCCP, FACS
Section Head of General Thoracic Surgery
Lung Cancer Surgery: When is it Necessary?

April 18th

Kathleen Newman, RD, CSO
Senior Clinical Dietician
Nutrition and Cancer Treatment

May 16th

Elizabeth A. David, MD
Minimally Invasive Lung Cancer Surgery: What Are We Doing Now, What’s on the Horizon?

June 20th

Valerie Kuderer, RN
Thoracic Surgery Nurse Coordinator
Recovery After Lung Cancer Surgery

July 18th

Karen Kelly, MD
Associate Director of Clinical Research
We Might Have a Clinical Trial for That

August 15th

Megan Daly, MD
Advances in Radiation Oncology

September 19th

Marlene von Friederichs-Fitzwater, PhD, MPH
WeCARE! Cancer Peer Navigation Program

October 17th

TBD

November 14th

Tina Li, MD
Personalizing Lung Cancer Therapy: How Tumor Molecular Testing Can Help Your Cancer Care